Chris Fernandez has a M.S. And I think that he saw that we had a level of determination that represented, “We’re gonna do this, whether or not he helped us and we’re gonna bang our heads a lot in the process.” And so I think that he convinced himself that he needed to save us some pain and became one of our earliest kind of mentors and advisors. and B.S. So we set out looking for a killer application. “Sleep apnea is a condition that plagues nearly one billion people worldwide, and we’re uniquely positioned to address this massive problem,” says Chris Fernandez, CEO of EnsoData, in a release. So for folks out there that like to jam, stop by any time, over under, not this year, unfortunately, really hopeful that by Q1 of next year, hopefully, early next year, we’re starting to have those opportunities. Chris Fernandez is the Co-Founder and CEO of EnsoData, the company using AI to more accurately diagnose health conditions. It seems so antiquated. And we’re seeing a lot of the growth in the sleep medicine industry, occurring in that push of patient care into the home setting in the home environment, both through home testing devices, through cloud-connected see pap devices, and through telehealth. He has acted as a leading contributor to the open source machine learning platform NEXT. Sam Rusk Founder. And my academic advisor told me at that time, “You’re doing too many things, you need to pick.” And a couple of days later, I had gotten to Y Combinators, first fellowship program, where they picked 35 companies out of more than 7,000 applicants to move out to the Bay Area and do that whole thing. things people say are impossible, but sort of just going for it is I think is a really big part of the battle. That company or that project ultimately went through more than a half dozen pivots. But I wanna hear the origin story, founder of, let’s hear the beginnings, Chris: So we wanna take it way back. And we’re like, “Why is nobody working on this?” And so that was sort of the toolset, the framework that we used when we went looking for that killer application. David Tenenbaum. Meb: I’m not gonna hold you to this. We wanna go wireless. Meb: Started the company with racking up a lot of frequent flyer miles on credit cards. By analyzing the waveforms found in sleep studies, EnsoData is able to accurately detect and diagnose sleep apnea and its related conditions. But, you know, I say that it’s 2020, and healthcare has really not benefited, you know, significantly yet from the AI revolution. Everybody’s looking for partnerships, and it’s kind of a circus. What’s next? Our guest is co-founder and CEO of EnsoData, a startup using AI and machine learning to analyze waveform data starting in the sleep space to save clinicians time on labour-intensive, complex, data interpretation and help them across the healthcare continuum. There are alternatives as well. I highly encourage folks to check us out there and to dig into our research more funds. EnsoData’s technology unlocks the vast wealth of clinical expertise lying dormant in archived data. So we had somebody that was phenomenally experienced in medicine, venture capital, startups, and kind of running a business. Chris has 7 jobs listed on their profile. Come with me. Chris: I can share the single biggest and most important lesson that I’ve learned about sleep personally in my life, and I learned that lesson during college before we were playing work on sleep, back, if you pulled me out of the time machine and you asked me if I thought that sleep is gonna be fine. We were able to raise so we close twice as much money as we set out to raise we closed $9 million, and then included Zetta Venture Partners, one of the best AI-focused kind of seed-stage funds that’s out there with great expertise in healthcare. Everybody who’s tried it has had a horrible experience, flatly they don’t believe it back in 2015. Founded in 2015, EnsoData provides software-­as-­a-­service (SaaS) that enables the discovery, identification, and actionable reporting of critical to … EnsoData CEO and co-founder Chris Fernandez is one of EnsoData’s three code wizards. And I think that comes in how comfortable is the device? And so it’s excellent. Pictured above are, from left to right: Nick Glattard, co-founder and chief technical officer; Sam Rusk, co-founder and president; Brock Hensen, chief operating officer; and Chris Fernandez, co-founder and CEO, along with Murph, the office dog. Email Justin at jb@cambriainvestments.com. Chris Fernandez 20+ Year Internet Marketing, Health And Fitness Expert; Owner and CEO Of Women's Health Interactive. And just to prove that our product worked, we needed several hundred thousand dollars. Meb: So a lot of fun hearing about this. Chris: We ultimately got our FDA 510K clearance to aid clinicians in diagnosing sleep apnea and other sleep disorders by automating the analysis of the physiologic waveform data that came from sleep studies. Chris Fernandez Senior Project Manager - Azure Cloud Infrastructure / … We do envision wearables as being an important mechanism for patients and consumers to be able to access information about how they sleep and how they can improve it. It’s more comfortable. I was last, of course, out of hundreds of people. Had you graduated? I got much better grades, I was much more productive and I was much happier. What is the actual treatment? We got to around three live customers with around six sleep clinics by the end of 2017. We don’t have anything we can give you. Like, I shared a little bit on, you know, within sleep specifically, where else outside of the diagnosis? We said good. Biomedical engineering is incredibly broad. And then it’s been scaling since then. All right. We were ready to go, kind of do the FDA thing and that required capital. We wanna use this powerful machine learning. And so we pivoted to trying to sell that technology to other medical device companies. Courtesy of EnsoData. We walk through the origin story of EnsoData, from the founders’ initial idea followed by 12 pivots to arrive at their flagship product, EnsoSleep. We kind of clash and meet somewhere in the middle. Chris: So, now, we’re in 2014. Chris Fernandez is a filmmaker and graphic designer, currently studying BA Film at the University of Westminster in London. Hyliion has developed patent pending hybrid electric system for Semi-Trailers and Trucking Industry. Chris: That was the Dick’s Sporting Goods arena that time. You know, it was something that we didn’t have, you know, a ton of direct experience with. And so, the clinics that were already well-equipped and at scale in-home testing, many of them [inaudible 00:27:08]. Chris Fernandez. I was a fellow biomedical engineer. Chris Fernandez Co-founder & CEO at EnsoData. And there was, like, one project left. I’m actually getting ready to hit the road. Chris Fernandez Founder and CEO, EnsoData. You know, sleep studies can range from anywhere between a half gigabyte to five gigabytes each. One of my favorite research papers on artificial intelligence and healthcare was done by researchers at the University of Chicago. Meb: Podcast listeners, we’ll post show notes to today’s conversation at mebfaber.com/podcast. On those sensors, they are reading these this data in 32nd pages. My current favorite is Breaker. You guys did an early raise and you guys just raised another big slug. And I think there’s been a lot of evolution in the public, you know, just with all the dialogue there and all the news on artificial intelligence, that’s been very influential in sort of the evolution of adoption in a clinician’s mindsets. Sleep disorders are often indicative of broader health problems, such as obesity, depression, diabetes or stroke, said EnsoData CEO and co-founder Chris Fernandez. Meb: It’s such an obvious why in the world any clinician would be spending all this time reviewing these mounds of data. And now we live in a world with, you know, more data than we conceived that we could even store a decade ago. SleepScore Ventures was also in the round, one of the first sleep-focused venture capital funds that has a lot of amazing strategic relationships, and others, you know, including Dreamit Ventures, a VC fund associated with one of the accelerators that we did, which is awesome. You take courses in chemistry, and physics, and biology, and statistics, and mathematics, and every other engineering discipline, from mechanical engineering, to electrical engineering, computer engineering. Chris Fernandez. How far are we away from…? Chris Fernandez, EnsoData Businesses that offer HST logistics have been popular. And some treatments may just not kind of totally circumvent the underlying reason, the underlying causes. I think that’s the art and the science. Here’s the kind of the bunk where we do all this work. And that really kind of helped us to accelerate that fundraise process. Chris Fernandez has a M.S. Tyne & Wear. That’s a separate story. Meb: As most of the sleep clinics you go to, right, it’s in-person where you go and get tested. In today’s episode, we’re talking all things sleep. But how difficult is it to say, “Okay, we’re gonna look at this totally different data set. My recommendation to any and every healthcare founder is raise there because it’s the beginning of the year, everybody’s sort of like, they got the fresh books. Meb Faber Research – Stock Market and Investing Blog, Why We Sleep: Unlocking the Power of Sleep and Dreams (Walker), The Sleep Revolution: Transforming Your Life, One Night at a Time (Huffington), Episode #238: Mark Straub, Smile Identity, “Face Recognition Is, In A Sense, Deep Technology”, Episode #240: Stefan Batory, Booksy, “This Is Probably The Last Major Vertical That’s Not Digitalized…And This Is A Massive Space”, Episode #274: Mitch Baruchowitz, Merida Capital Holdings, “Is The Trade Over? And a lot of people had tried to adapt quickly. Is there also any sort of at-home sort of diagnostic or is there any sort of kits on the horizon where people could self-test at all or what’s the lay of the land for sleep clinic base, in general? We’re heading to see some family in Colorado, in Utah, and Wyoming. Since inception, it has seen 100 percent customer retention, he said. They wanna follow along with the story. Chris: The thing I would say is I think it’s so important for startup companies to be driven by real purpose and mission. Don’t you know better than we?” That was a lesson. Chris: Go to market, sales. So there’s a big push in what they call phenotyping or endotyping diseases, to take them to the next level of resolution, to be able to understand what individual or combinations of factors are most likely causing those diseases and being able to take a much more targeted and personalized approach to, you know, really trying to address the root cause. There’s two parts to that answer. Episode #239: Chris Fernandez, EnsoData, “There Was One Particular Area That Felt Like It Was At Least 5 Years Behind…And That Was The Application Of AI To Waveform Data”. You know, it’s a little hard, but one of the most effective ways to lose 10% of your body weight, in many cases, that has a meaningful impact on the severity of the sleep apnea but we lost as hard. It includes two kinds of airflow to be able to measure breathing and breathing frequency. Tyne & Wear. So listeners, if you wanna do, like, a 10-foot meetup, shoot me a message, and we can grab a beer somewhere. But as I was thinking about this podcast, my brother… I mean, there’s at least three or four people in my family that probably have sleep apnea, whether they know it or not. Meb: It’s all right we’ll have you back next year or whenever and you can chat about all these things. Chris: So typically, first line of defense for a patient that has obstructive sleep apnea would be CPAP therapy, which is continuous positive airway pressure therapy. “This joint collaboration will enable our technology-driven companies to accelerate innovation in the field of sleep medicine, leading to new developments to transform the delivery of care and enable clinicians to spend more time personalizing patient care and less time on data in a way that improves access, outcomes, satisfaction and costs,” said Chris Fernandez, EnsoData’s CEO. Meb: I used to go to the JP Morgan conference every year so I actually started out as a biotech equity analyst in the depths of the last big internet biotech busts. And for all the folks out there that are AI people, you know, it’s a lot more fun to apply AI to a mission like this, then do we put up the Bears jersey or the Packers jersey? I highly recommend Dreamit as well, and Necessary Ventures, HealthX Ventures, Fully Capitalist. How do we wrap that in a nice kind of patient experience? Chris Fernandez. We saw the microprocessor try to come out around the ’50s, and we got personal computers. And so that was an early signal that this was a good idea. See the complete profile on LinkedIn and discover Chris’ connections and jobs at similar companies. You know, there are more advanced versions of PAP therapy, as those conditions get more severe and complex. I would say I learned a lot of lessons. And that was like the needle that seemed impossible. What’s your hacks? Meb: Supposed to be a world-class university town, I’ve never been. No sleeping on today’s show. Today’s episode, we drink some Red Bulls and talk all things sleep. When you find something, when there’s a billion people that have it, and they don’t know yet, that felt like a really unique opportunity to try to massively scale up patient access to information about how they sleep, how to do it better, and, you know, how it affects them. Please enjoy this episode with EnsoData’s, Chris Fernandez. Were you still in school at this point? We had an amazing mentor and advisor, Dr. Fred Robinson, who’d initially sponsored that project, read, kind of prior to being an anesthesiology professor at the University, was previously the CEO of Marquette Medical Systems, helped to sell that to GE, served as their chief clinical officer, and then went on to serve as CEO of TomoTherapy through their IPO and eventual exit to Accuray. We put together a team of very experienced advisors and consultants to help kind of guide us and point us in the right direction. As it turns out, we also loved working together and wanted to turn these passions into something tangible. If you love the show, if you hate it, shoot us feedback@themebfabershow.com. Summary: In episode 239 we welcome our guest, Chris Fernandez, co-founder and CEO of EnsoData. Chris Fernandez. That’s an area that we’re really excited about. I really appreciate the opportunity, huge fan of the show and excited to continue listening and following along. Chris: You know, I think from an FDA standpoint, it’s different for each different kind of product. Same platform but with new and improved features. We come back from Y Combinator, we’re pre-funding. We’ve done some initial validation of our software in several areas outside. Who’s gonna do sales?” And they both just point at me like, “You.” So I was unanimously elected to do sales. Chris Fernandez is the co-founder and CEO of EnsoData, a company that uses artificial intelligence (AI) to simplify the process of accurately diagnosing health conditions. So you’re talking about dozens of different kinds of sensors. Chris Fernandez is CEO/Co-Founder at EnsoData Inc. See Chris Fernandez's compensation, career history, education, & memberships. We picked it and then the professor said, “Ha, the hardest project, like, all right, here we go.”. And then there’s a raffle and kind of what order you get to choose it. And from our perspective, we as a field should put the right practices in place so that this pandemic or the inevitable next pandemic, whenever that does happen, is not something that causes patients to lose access to healthcare because it simply doesn’t need to . it was the busiest couple days ever. And that includes things like five different kinds of sleep stages, apneas, hypopneas, blood oxygen, saturations, neurological arousals, bradycardia, tachycardia. And, you know, of course, as we said with the current kind of compliance levels on CPAP, we’re really trying to support pharma companies and medical device companies in bringing forward that next generation of more patient-friendly, more comfortable treatment options that folks have more to choose from. Where do they go? I’m glad that we took the advice to stay in school because when we graduated, I felt an inch deep and a mile wide. So I think that we feel really, really lucky to have been able to, you know, secure this financing during the pandemic, during tremendous economic uncertainty. I think there’s a lot of really talented people out there that just purely do the external environment of COVID, have been put into place where they’re either out looking for work or the place that they’re working, it’s become, you know, a little bit less enjoyable. My wife doesn’t. So, we couldn’t raise money to do the hardware business. You know, in the first half of college, let’s call it, I was frequently staying up until 2:00 am to try to study for tests, stay on top of deadlines and projects. We did a half-million dollars on seriously financing in early 2016. And that was the application of AI to waveform. You can weather that storm. But to do really fancy machine learning and deep learning, you’re really talking about terabytes, and petabytes, exabytes scale data. So on average, that takes about an hour or an hour for an in-lab sleep study. So, we decided to leverage a free trial model, like many or most SaaS solutions do to drive customer acquisition. They have broad expertise in the healthcare industry in these different segments. In episode 239 we welcome our guest, Chris Fernandez, co-founder and CEO of EnsoData. You know, we were initially arguing to raise about 5 million. And main drivers in that adoption of home testing are, you know, a lot of patients feels more comfortable. No…It’s Just Getting Going In Some Ways”. That’s at the beginning of the year in January. Meb: What’s the current gold standard for apnea? EnsoData, whose software uses machine learning algorithms to help clinicians score sleep data and diagnose patients with sleep apnea and other … And, you know, when you’re talking about sleep apnea, ultimately, you’re talking about hundreds of thousands of events per patient that need to be manually done. But ultimately folks advised that if you wanna do a business like this in healthcare, it’s generally nice to have, to some kind of a degree, you should probably finish that, he said. It wasn’t a super exciting exit, but it was a cool experience. Chris: There’s a few different directions. Today, they’re 80% to 90% undiagnosed. Where would we be now? Other, you know, options and alternatives include oral appliances to sort of create the right spacing in the mouth for that breathing to happen. Today's guest is Chris Fernandez, CEO and co-founder at EnsoData. So that was really a crossroads. Founder EnsoData • Worked at @ Innovative Signal Analysis, @ Hitachi Global Storage Technologies • Studied at @ University Of Wisconsin Madison. And so there’s a huge list of projects. And so I think that’s just an example of some of the categories and tools that are available in machine learning and AI that aim to address that problem directly. I don’t know how many laps I’ve made through it yet, but more than 10. And then they did this procedure that we called transfer learning to try to use what the AI had learned about pulling out useful information, structures, regularities, patterns out of that format of imaging data, and to just try to generalize and borrow some of those learnings to apply it so that they could juice up performance on this much smaller data set. But sort of along the way, it may be helpful to walk through the pivots to contextualize what we do. In today’s episode, we’re talking all things sleep. But initially, the go-to-market, the three of us sat down and were like, “All right, now we can sell it. Can you walk through kind of where we are here in 2020, what other fun expansions either this analysis or other things you guys are looking at to the extent you can talk about it? We went through… So I guess after that, we were sort of at a crossroads between staying in graduate school or do we cut and run. It’s like, how are you gonna spend more time sleeping and then how are you gonna account for that on the other side? You know, we had several technological revolutions leading up to it and enabling it. Chris Fernandez Founder. That was co-led by venture investors as well. At an event last August featuring pitches from startups, EnsoData co-founder Chris Fernandez told audience members that … And I found myself really tired a lot, and all that, and tried to do an experiment which was feels like I’m really not being as productive as I could be. I think we’ve really been able to leverage that in a variety of different ways from solving that data, chicken or egg problem to recruiting, you know, some of the best people in the world. Curated profile of Chris Fernandez, Co-founder & CEO, EnsoData including career history, news and intelligence, portfolio companies and investments. Thank you for accessing our content on the Topio Networks Market Intelligence Center. So you guys kind of are working your way through the problem, trying to find this product-market fit. Total raised $2M. Do you know what I’m talking about? What else you learned about sleep that might be helpful for our listeners? And I think it’s been really exciting to kind of follow, you know, some of those developments, as well. Excited to be here. And in critical care unit, it includes electrocardiograms that are used to diagnose cardiac conditions. “Sleep apnea is a condition that plagues nearly one billion people worldwide, and we’re uniquely positioned to address this massive problem,” said Chris Fernandez, CEO of EnsoData. So you get to taste everything. Together, along with my co-founders Chris Fernandez and Nick Glattard, we founded EnsoData, the company using groundbreaking AI to simplify the process of analyzing the human body to diagnose health conditions, starting with sleep. If you could solve this problem, be broadly applicable, be applicable immediately, be applicable to every sleep clinic in the U.S. and globally, and I want it so bad, I’ll give you 3,000 patients worth of data to see if it works.” And so people are literally trying to give us their data. And then in the 2000s, we started seeing adoption. When we are… This is July 1st, we’re recording this, it seems like you’re a music fan. There are 700+ professionals named "Chris Fernandez", who use LinkedIn to exchange information, ideas, and opportunities. In order to launch a hardware business, especially an FDA regulated hardware business, that requires upfront capital. Chris Fernandez Senior Project Manager - Azure Cloud Infrastructure / 0365. Episode #272: Best Idea Show – Tobias Carlisle, Acquirers Fund, “There Are Basically Three Big Periods Of Value Underperformance And They Seem To Congregate... 1:32 – Welcome to our guest, Chris Fernandez, 20:30 – How the clinicians responded to their data, 25:17 – An overview of the sleep clinic space and its evolution, 44:36 – Other places where AI can help in healthcare, 46:14 – Most memorable moment of the startup journey. Meb: Okay. Thanks for listening, friends, and good investing. Founded in 2015, EnsoData provides software-­as-­a-­service (SaaS) that enables the discovery, identification, and actionable reporting of critical to understand patterns and trends in health data. I initially, you know, met my co-founders at the University of Wisconsin, Madison back in 2010. What are we gonna do with it?” And we said, “I don’t know. And more than a billion waveform studies run per year to diagnose, monitor and treat patients in nearly every speciality of medicine. Since EnsoData’s founding in 2015, Chris and the EnsoData team have delivered 8 accepted peer-reviewed AI research presentations at leading AI/ML and Medicine conferences including NIPS Annual Conference on Neural Information Processing Systems, American Academy of Sleep Medicine's Annual SLEEP Conference, IEEE's International Engineering in Medicine and Biology Conference, and more. Arianna Huffington ended up writing a sleep book. I think the great thing about wearables is, you know, sleep is really not just a thing for patients. Meb: Well, we’re gonna talk about all things sleep today. Nobody has cracked the nut. I got heavily schooled in at the end of it because my VME masters ended up being mine computer science classes, right? Fernandez used his expertise to Coding and writing in the car was a very common occurrence for us at the early stages as we parallel across those words. And using that capacity to focus on wanting to continuing to expand our partnerships with our core customers and others in the industry, as well as bringing new products to market that are really going to change things. And that was a much better, more sustainable, and more productive way to approach things. Meb: Awesome, Chris, people wanna find out more about what you guys are up to. That point we still had three people. I’m a tiny investor in this last round of years, last year, oddly enough to buy about a round of what you’d say? Anywhere good podcasts are found. And we saw an opportunity by applying waveforms to dramatically improve patient access, patient outcomes, the in-patient provider experience and the affordability of healthcare. So I highly recommend it. Fernandez used his expertise to design and then clinically validate EnsoData’s pioneering technology, Waveform AI. Sirj Goswami, PhD Founder and CEO, InsightRx. Prior to EnsoData, Chris was CEO of a social custom apparel marketplace Langdon Co., where he grew the business and oversaw its successful acquisition within its first year. We interviewed more than 100 different physicians from every specialty of medicine, haematology, hepatology, endocrinology, all the fancy and esoteric specialities, and found an amazing problem, and an opportunity in the world of sleep. Spoke Intelligence is home of VB Profiles. What novel sensors can we add to it? Meb: My family lives sort of near Morrison. Congressman Chet Edwards of Waco, Texas – 17th Congressional district. Chris: Howdounsedated.com, we publish blogs. www.vbprofiles.com is now www.topionetworks.com. We get into the long-term vision for the company, and even the potential for transferability of their algorithms in AI into other areas outside of sleep. And we then hired our COO, Brock from Epic systems. Why don’t we embrace this opportunity, try to do it better than everybody else, try to innovate inside of it, and try to use this to kind of push it forward faster, and to create differentiation? Thanks so much for joining us today. We said, “We’re living…” Our co-founder and I were living in a dingy apartment that we had negotiated a month to month rent on, and I was getting close to maxing out the credit card. It’s a totally different game. You mentioned with the EKG, and the pulse oximeter, and everything. In today’s episode, we’re talking all things sleep. We talk about analyzing sleep data, solving hard data analysis problems with AI, and bootstrapping enough data into data ecosystem to build and validate the product. Pages of software documentation that summer that had one of EnsoData from systems! Guess we ’ ve done some initial validation of our software in several areas outside the try! Cto and I want more people to have that up too to YC, ” that was a easier! 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